Three puzzles in the history of smallpox in Latin America
1. Smallpox and catastrophe: What was the role of smallpox in the demog. catastrophe? 2. Genes or exploitation and experience: Why did natives suffer so greatly from the disease?
3. Smallpox and recovery: Did smallpox become less virulent? What was the effect of public health campaigns (quarantine inoculation, and vaccination), versus population densities on smallpox mortality.