Evidence from chronologies and parish burial books
Recall 17 epidemics 1520-1745: 7 in 16th century; 6 in 17th c; 4 in 18th to 1746; only 3 of smallpox: 1520, 1538, 1733/34.
18th century was the century of smallpox epidemics in Mexico: 1733/4, 1761/62, 1779, 1797.
Evidence from parish burial books (Mexico): Center (Puebla), South (Chiapas), and North (Chihuahua).